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Table 2 Genotype distribution and crude ORs

From: LINE-1 global DNA methylation, iron homeostasis genes, sex and age in sudden sensorineural hearing loss (SSNHL)

 

SLC40A1 − 8CG

(rs11568351)

SOD2 A16V

c.47C > T (rs4880)

Cases

n = 206

(%)

CC

127

(61.6)

CG

62

(30.1)

GG

17

(8.25)

CC

43

(20.9)

CT

97

(47.1)

TT

66

(32.0)

Genotype distribution (P)

0.005

0.09

OR

D-model (P)

1.18 (0.83–1.77); n.s

1.31 (0.88–1.96); n.s

OR

R-model (P)

3.34 (1.54–7.29); 0.0015

1.47 (1.02–2.12); 0.037

OR

Allele (P)

1.31 (1.01–1.79); 0.037

1.28 (1.02–1.63); 0.036

Controls

n = 420

(%)

CC

276

(65.7)

CG

133

(31.7)

GG

11

(2.6)

CC

108

(25.7)

CT

210

(50.0)

TT

102

(24.3)

  1. OR D-model and R-model indicate dominant and recessive model comparison, respectively. The significant P-values and ORs are marked in bold