Table 2 The prioritized BP-associated genes based on the integrated GWAS score (Criterion 1)

1

ULK4

81

276

13

100

36

FTO

21

103

4

29.9

71

CERS5

50

1

3

20.4

2

ATP2B1

170

44

18

99.5

37

ADRB1

58

1

6

28.5

72

CEP164

34

6

6

20.3

3

SH2B3

180

5

11

84.1

38

HOXC4

41

26

7

28.4

73

C1orf167

45

10

3

20.1

4

ATXN2

180

22

8

82.1

39

LRRC10B

46

4

8

27.9

74

MBD5

58

1

1

20

5

ZNF831

79

124

11

67.8

40

CDH13

51

2

7

27.8

75

ARVCF

28

7

7

19.9

6

CNNM2

87

59

14

63.9

41

WNT2B

42

18

7

27.3

76

ADAMTS8

52

2

2

19.6

7

CLCN6

109

79

6

62.3

42

PLCE1

46

8

7

27

77

NAA25

42

4

4

19.6

8

MTHFR

104

29

10

58

43

FGF5

57

3

5

26.8

78

SUGCT

28

5

7

19.6

9

CABCOCO1

88

58

10

57.3

44

ST7L

42

32

5

26.5

79

TNNT3

45

6

3

19.4

10

CSK

98

19

10

53.9

45

FURIN

50

11

5

25.6

80

UGT2A1

56

1

1

19.2

11

NT5C2

89

45

9

53.5

46

PDE1A

39

23

6

25.4

81

FBN2

30

5

6

18.6

12

ARHGAP42

87

18

12

52.9

47

PLEKHG1

46

7

6

25.1

82

PHACTR1

36

1

5

18.5

13

CACNB2

78

50

10

52

48

ZFAT

44

8

6

24.5

83

XKR6

22

48

3

18.4

14

FES

84

15

11

49.5

49

AGT

40

6

7

24.3

84

ABHD17C

28

6

6

18.1

15

SLC39A8

88

1

10

46.7

50

ARHGAP24

35

7

8

24.3

85

DBH

34

2

5

17.9

16

LSP1

73

24

9

43.6

51

ESR1

47

7

5

23.7

86

PTPN11

41

6

3

17.9

17

LMAN1L

99

9

4

42.2

52

CFDP1

32

9

8

23.5

87

SCAMP2

36

16

3

17.8

18

MECOM

57

36

10

41.4

53

COL21A1

36

10

7

23.5

88

ZNF318

24

22

5

17.8

19

CASZ1

56

10

13

41.4

54

PINX1

25

68

3

23.2

89

ANK2

52

1

1

17.7

20

INSR

66

16

10

41.2

55

SWAP70

36

6

7

22.8

90

VARS

47

2

2

17.7

21

GOSR2

71

2

10

40.5

56

PLEKHA7

20

18

9

22.4

91

FN1

33

3

5

17.7

22

RGL3

82

2

7

39.5

57

SIPA1

34

6

7

22

92

NMT1

37

4

4

17.7

23

SOX6

49

46

9

38.5

58

GUCY1A1

32

10

7

22

93

SBF2

36

15

3

17.6

24

MSRA

49

82

5

38.4

59

TRAPPC9

32

9

7

21.8

94

PFKM

51

1

1

17.3

25

NOS3

77

2

7

37.6

60

CUX2

48

3

4

21.7

95

EBF1

34

7

4

17.1

26

NPPA

81

7

5

36.7

61

SLC14A2

43

4

5

21.7

96

HOXC6

41

11

2

17.1

27

CTNNA3

89

5

3

35.9

62

AS3MT

45

18

3

21.6

97

PDILT

45

1

2

16.8

28

KCNK3

62

11

8

35.3

63

FGD5

26

10

8

21.4

98

CACNA1D

22

11

6

16.7

29

CCN3

86

1

3

34

64

MYH6

47

2

4

21.1

99

VAC14

44

2

2

16.6

30

HFE

57

5

8

32.3

65

PAX2

46

4

4

21.1

100

BORCS7

35

2

4

16.6

31

CYP17A1

71

3

5

32.1

66

SLC24A3

36

6

6

21.1

101

EBF2

34

4

4

16.5

32

NOX4

51

5

9

31.7

67

COX14

51

2

3

20.9

102

JCAD

30

2

5

16.4

33

SLC4A7

23

85

6

30.7

68

CAPZA1

41

4

5

20.9

103

PRDM6

28

6

5

16.3

34

NPR3

75

5

3

30.6

69

CDK6

45

3

4

20.5

35

SDCCAG8

41

44

6

30

70

DOT1L

30

6

7

20.5