Table 1 Association of rs479200 and rs516651 in the EGLN1 gene with clinical and demographic characteristics (Regression (logistic) analysis)
Wald | Sig | Odds Ratio | Confidence interval | |||
|---|---|---|---|---|---|---|
Asymptomatic versus mild | ||||||
rs479200 T > C | Dominant (CC + CT vs TT) | Unadjusted | 0.388 | 0.533 | 1.327 | (0.545–3.23) |
Adjusted | 0.111 | 0.739 | 1.172 | (0.461–2.976) | ||
Recessive (CC vs CT + TT) | Unadjusted | 0 | 0.992 | 0.995 | (0.369–2.68) | |
Adjusted | 0.003 | 0.956 | 0.971 | (0.349–2.707) | ||
Additive (TT vs CT; TT vs CC) | Unadjusted TT vs CT | 0.438 | 0.508 | 1.375 | (0.535–3.532) | |
Unadjusted TT vs CC | 0.113 | 0.737 | 1.219 | (0.384–3.871) | ||
Adjusted TT vs CT | 0.135 | 0.713 | 1.201 | (0.451–3.197) | ||
Adjusted TT vs CC | 0.023 | 0.88 | 1.098 | (0.326–3.696) | ||
rs516651 C > T | Dominant (CC vs CT + TT) | Unadjusted | 0.076 | 0.783 | 1.238 | (0.271–5.653) |
Adjusted | 0.047 | 0.828 | 0.844 | (0.183–3.899) | ||
Asymptomatic versus severe | ||||||
rs479200 T > C | Dominant (CC + CT vs TT) | Unadjusted | 6.723 | 0.01* | 3.956 | (1.399–11.188) |
Adjusted | 6.915 | 0.009* | 6.024 | (1.58–22.967) | ||
Recessive (CC vs CT + TT) | Unadjusted | 5.045 | 0.025* | 2.862 | (1.143–7.163) | |
Adjusted | 3.705 | 0.054 | 2.798 | (0.981–7.98) | ||
Additive (TT vs CT; TT vs CC) | Unadjusted TT vs CT | 3.733 | 0.053 | 2.952 | (0.984–8.854) | |
Unadjusted TT vs CC | 8.653 | 0.003* | 6.214 | (1.84–20.99) | ||
Adjusted TT vs CT | 4.893 | 0.027* | 4.779 | (1.195–19.108) | ||
Adjusted TT vs CC | 8.145 | 0.004* | 9.421 | (2.019–43.957) | ||
rs516651 C > T | Dominant (CC vs CT + TT) | Unadjusted | 0.531 | 0.466 | 0.6 | (0.152–2.369) |
Adjusted | 1.305 | 0.253 | 0.42 | (0.095–1.86) | ||