Fig. 5
From: Evolutionary origin of germline pathogenic variants in human DNA mismatch repair genes
Geographical distribution of the ancient human fossils sharing MMR PVs in modern humans. White dot: ancient fossils identified; colored circles: ancient human individual with MLH1 PVs; colored squares: ancient human individual with MSH2 PVs; colored diamonds: ancient human individual with MSH6 PVs; colored pentagrams: ancient human individual with PMS2 PVs. The color line at the bottom shows the timing distribution of the ancient fossils sharing MMR PVs in modern humans