Table 1 Summary of the neurosurgical disorders datasets
From: Causal associations of COVID‐19 on neurosurgical diseases risk: a Mendelian randomization study
Neurosurgical disorders | Diseases | Cases | Controls | Sample size | SNPs | Population | Year | Dataset |
|---|---|---|---|---|---|---|---|---|
Cerebrovascular diseases | Trigeminal neuralgia | 800 | 195,047 | 195,847 | 16,380,408 | European | 2021 | finn-b-G6_TRINEU |
Epilepsy | 4,382 | 453,928 | 458,310 | 24,186,492 | European | 2021 | ebi-a-GCST90018840 | |
Parkinson’s disease | 2,638 | 477,380 | 480,018 | 24,194,622 | European | 2021 | ebi-a-GCST90018894 | |
Alzheimer’s disease | 39,106 | 46,828 | 487,511 | 20,921,626 | European | 2022 | ebi-a-GCST90027158 | |
Major depressive disorder | 7,264 | 49,373 | 56,637 | 11,498,420 | European | 2021 | ebi-a-GCST90086059 | |
Obsessive Compulsive Disorder | 26,888 | 7,037 | 33,925 | 8,409,517 | European | 2017 | ieu-a-1189 | |
Functional diseases | Stroke | 40,585 | 406,111 | 446,696 | 7,633,440 | European | 2018 | ebi-a-GCST005838 |
Intracerebral hemorrhage | 1,935 | 471,578 | 473,513 | 24,191,284 | European | 2021 | ebi-a-GCST90018870 | |
Subarachnoid hemorrhage | 1,693 | 471,562 | 473,255 | 24,191,735 | European | 2021 | ebi-a-GCST90018923 | |
Transient ischemic attack | 8,835 | 205,799 | 214,634 | 16,380,437 | European | 2021 | finn-b-G6_TIA | |
Cerebral infarction | 2,353 | 358,841 | 361,194 | 10,889,323 | European | 2018 | ukb-d-I63 | |
Cerebral aneurysm | 945 | 472,738 | 473,683 | 24,191,145 | European | 2021 | ebi-a-GCST90018815 | |
Spinal and spinal cord disease | Cervical spondylosis | 3,352 | 481,246 | 484,598 | 9,587,836 | NA | 2021 | ebi-a-GCST90038693 |
Spinal canal stenosis | 9,660 | 445,127 | 454,787 | 24,182,979 | European | 2021 | ebi-a-GCST90018922 | |
spinal meningioma | 118 | 218,674 | 218,792 | 16,380,466 | European | 2021 | finn-b-CD2_BENIGN_MENINGES_SPINAL | |
Spinal osteochondrosis | 183 | 164,682 | 164,865 | 16,380,216 | European | 2021 | finn-b-M13_SPINALOSTEOCHON | |
Intracranial and intraspinal abscess | 141 | 217,485 | 217,626 | 16,380,461 | European | 2021 | finn-b-G6_CNSABSC | |
Cervical spinal cord and nerve injuries | 254 | 215,476 | 215,730 | 16,380,463 | European | 2021 | finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL | |
Central nervous system neoplasms | Glioblastoma | 91 | 218,701 | 218,792 | 16,380,466 | European | 2021 | finn-b-C3_GBM |
Benign meningioma | 1,147 | 217,645 | 218,792 | 16,380,466 | European | 2021 | finn-b-CD2_BENIGN_MENINGES_CEREBRAL | |
Malignant meningioma | 640 | 218,152 | 218,792 | 16,380,466 | European | 2021 | finn-b-C3_MENINGES | |
Pituitary adenoma and craniopharyngioma | 735 | 218,057 | 218,792 | 16,380,466 | European | 2021 | finn-b-CD2_BENIGN_PITUITARY_CRANIPHAR | |
Benign neoplasm of brain and other parts of CNS | 923 | 217,869 | 218,792 | 16,380,466 | European | 2021 | finn-b-CD2_BENIGN_BRAIN_CNS | |
Malignant neoplasm of brain and other parts of CNS | 198 | 218,594 | 218,792 | 16,380,466 | European | 2021 | finn-b-C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS | |
Other brain diseases | Hydrocephalus | 749 | 205,799 | 206,548 | 16,380,404 | European | 2021 | finn-b-G6_HYDROCEPH |
Craniosynostosis | 405 | 218,387 | 218,792 | 16,380,466 | European | 2021 | finn-b-Q17_CRANIOSYNOSTOSIS | |
Concussion | 10,527 | 136,576 | 147,103 | 16,380,074 | European | 2021 | finn-b-ST19_CONCUSSION | |
Diffuse brain injury | 656 | 136,576 | 137,232 | 16,379,965 | European | 2021 | finn-b-ST19_DIFFU_BRAIN_INJURY | |
Focal brain injury | 1,065 | 136,576 | 137,641 | 16,379,970 | European | 2021 | finn-b-ST19_FOCAL_BRAIN_INJURY | |
Congenital malformations of the nervous system | 258 | 218,534 | 218,792 | 16,380,466 | European | 2021 | finn-b-Q17_CONGEN_MALFO_NERVOUS_SYSTEM |