Fig. 3
From: Solanidine is a sensitive and specific dietary biomarker for CYP2D6 activity
Performance of plasma biomarkers in detecting different CYP2D6 phenotypes. AUPRCs represent the trade-off of precision and sensitivity for every possible cutoff value. Horizontal dashed lines (a, c, e) represent the baseline AUPRC values, which correspond to the proportions of gPM, gIM, and gUM phenotypes. AUROCs show relationships between sensitivity and specificity for every possible cutoff value. Dashed lines (b, d, f) represent random classifier. AUPRC, area under the precision–recall curve; AUROC, area under the receiver operating characteristic curve; gIM, intermediate metabolizer; gPM, poor metabolizer; gUM ultrarapid metabolizer