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Fig. 3 | Human Genomics

Fig. 3

From: Cellular and clinical impact of protein phosphatase enzyme epigenetic silencing in multiple cancer tissues

Fig. 3

Cancer-associated epimutations are commonly observed in Protein Tyrosine (PTP) and Dual-Specificity Phosphatase (DUSP) gene promoters. A-B. Bar graph demonstrating the % of individuals in each cancer subtype that carry at least one cancer-specific epimutation in tyrosine (A, blue) and dual specificity (B, green) phosphatase gene promoters. C-D. Bar graph representing the most ubiquitous PTP (C) and DUSP (D) gene promoters that harbour cancer-specific hyper-methylated promoters. Numbers above each bar represents % of cancer individuals with epimutations in the genes highlighted on the x-axis. The genes represented in (C) and (D) were detected in at least 5 individuals

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Human Genomics

ISSN: 1479-7364