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Table 1 Frequencies of SLCO1B1 diplotypes and their associated CPIC phenotypes in the Saudi population

From: Large-scale next generation sequencing based analysis of SLCO1B1 pharmacogenetics variants in the Saudi population

SLCO1B1 Diplotype

SLCO1B1 Phenotype*

Total (n = 1928)

Percentage of the population

*1/*1

Normal Function

18.05%

*1/*14

Normal Function

5.50%

*1/*20

Normal Function

7.26%

*1/*37

Normal Function

9.96%

*14/*37

Normal Function

1.82%

*20/*37

Normal Function

2.44%

*37/*37

Normal Function

3.16%

*1/*5

Decreased Function

3.68%

*1/*15

Decreased Function

21.32%

*1/*31

Decreased Function

0.21%

*5/*14

Decreased Function

0.36%

*5/*20

Decreased Function

0.05%

*5/*37

Decreased Function

1.04%

*9/*20

Decreased Function

0.05%

*14/*15

Decreased Function

2.65%

*14/*31

Decreased Function

0.05%

*15/*20

Decreased Function

3.48%

*15/*37

Decreased Function

5.13%

*20/*31

Decreased Function

0.05%

*31/*37

Decreased Function

0.05%

*5/*5

Poor Function

0.26%

*5/*15

Poor Function

1.87%

*5/*31

Poor Function

0.05%

*15/*15

Poor Function

7.31%

*14/*14

Increased Function

0.41%

*14/*20

Increased Function

0.83%

*20/*20

Increased Function

1.24%

*1/*19

Indeterminate Function

0.41%

*1/*28

Indeterminate Function

0.05%

*1/*30

Indeterminate Function

0.10%

*1/*41

Indeterminate Function

0.21%

*4/*37

Indeterminate Function

0.26%

*5/*19

Indeterminate Function

0.05%

*5/*41

Indeterminate Function

0.05%

*14/*19

Indeterminate Function

0.05%

*15/*19

Indeterminate Function

0.21%

*15/*41

Indeterminate Function

0.21%

*19/*19

Indeterminate Function

0.10%

*19/*37

Indeterminate Function

0.10%

*20/*41

Indeterminate Function

0.05%

*37/*41

Indeterminate Function

0.16%