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Fig. 5 | Human Genomics

Fig. 5

From: Paternal aging impacts expression and epigenetic markers as early as the first embryonic tissue lineage differentiation

Fig. 5

Significant differentially expressed genes. Heat map representation of the hierarchical clustering of significant (q < 0.1) differentially expressed genes (DEGs) in (a) ICM (n = 145 DEGs) and (b) TE (n = 323 DEGs), where a positive z-score (red) corresponds to up-regulation and a negative z-score (blue) corresponds to down-regulation relative to the mean. Samples in both ICM and TE cluster into two distinct groups by young and APA samples

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