Table 1 APA ICM and TE significant differentially methylated regions (DMRs) and pathways
Young (34.3 ± 1.7 years) | APA Inner Cell Mass (ICM) | APA Trophectoderm (TE) | ||
|---|---|---|---|---|
APA (54.4 ± 3.3 years) | n=1,897 DMRs | n=2,022 DMRs | ||
| Â | Hypermethylated | Hypomethylated | Hypermethylated | Hypomethylated |
Total DMRs (p≤0.05) | 1713 | 180 | 1890 | 124 |
DMR-associated significant CpGs | 7771 | 936 | 14,061 | 892 |
DMR-associated Genes | 1114 | 130 | 1299 | 98 |
GO terms | 93 | 133 | ||
KEGG pathways | 0 | 25 | ||
Reactome | 6 | 4 | ||