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Table 8 Classification table

From: Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration

Prob.

level

Sensitivity

Specificity

PPV %

(5.5%)

NPV %

(5.5%)

PPV %

(10%)

NPV %

(10%)

PPV %

(15%)

NPV %

(15%)

0.00

100.0

0.0

5.5

--

10.0

--

15.0

--

0.02

99.8

0.2

5.5

94.5

10.0

90.0

15.0

85.0

0.04

99.8

2.1

5.6

99.4

10.2

99.0

15.2

98.3

0.06

99.8

4.3

5.7

99.7

10.4

99.5

15.5

99.2

0.08

98.8

8.6

5.9

99.2

10.7

98.5

16.0

97.6

0.10

98.1

12.0

6.1

99.1

11.0

98.3

16.4

97.3

0.12

97.7

15.0

6.3

99.1

11.3

98.3

16.9

97.4

0.14

97.3

18.2

6.5

99.1

11.7

98.4

17.3

97.4

0.16

96.7

20.8

6.6

99.1

11.9

98.3

17.7

97.3

0.18

95.9

23.8

6.8

99.0

12.3

98.1

18.2

97.0

0.20

95.0

29.1

7.2

99.0

13.0

98.1

19.1

97.1

0.22

93.6

33.0

7.5

98.9

13.4

97.9

19.8

96.7

0.24

92.9

38.1

8.0

98.9

14.3

98.0

20.9

96.8

0.26

91.7

43.3

8.6

98.9

15.2

97.9

22.2

96.7

0.28

90.5

45.2

8.8

98.8

15.5

97.7

22.6

96.4

0.30

88.8

48.8

9.2

98.7

16.2

97.5

23.4

96.1

0.32

86.9

50.7

9.3

98.5

16.4

97.2

23.7

95.6

0.34

86.1

53.7

9.8

98.5

17.1

97.2

24.7

95.6

0.36

85.5

56.7

10.3

98.5

18.0

97.2

25.8

95.7

0.38

83.4

60.4

10.9

98.4

19.0

97.0

27.1

95.4

0.40

81.7

63.2

11.4

98.3

19.8

96.9

28.1

95.1

0.42

80.5

65.3

11.9

98.3

20.5

96.8

29.0

95.0

0.44

78.4

66.6

12.0

98.1

20.7

96.5

29.3

94.6

0.46

77.8

68.1

12.4

98.1

21.3

96.5

30.1

94.6

0.48

73.7

71.7

13.2

97.9

22.4

96.1

31.5

93.9

0.50

72.4

74.7

14.3

97.9

24.1

96.1

33.6

93.9

0.52

70.3

75.4

14.3

97.8

24.1

95.8

33.5

93.5

0.54

68.9

76.0

14.3

97.7

24.2

95.7

33.6

93.3

0.56

68.5

76.9

14.7

97.7

24.8

95.6

34.4

93.3

0.58

63.9

79.9

15.6

97.4

26.1

95.2

35.9

92.6

0.60

61.4

84.6

18.8

97.4

30.7

95.2

41.3

92.5

0.62

60.4

85.4

19.4

97.4

31.5

95.1

42.2

92.4

0.64

58.3

86.1

19.6

97.3

31.8

94.9

42.5

92.1

0.66

56.6

87.6

21.0

97.2

33.7

94.8

44.6

92.0

0.68

51.5

89.1

21.6

96.9

34.4

94.3

45.5

91.2

0.70

50.0

90.4

23.3

96.9

36.7

94.2

47.9

91.1

0.72

47.7

91.4

24.4

96.8

38.1

94.0

49.5

90.8

0.74

44.6

92.3

25.2

96.6

39.2

93.7

50.5

90.4

0.76

43.8

92.9

26.4

96.6

40.7

93.7

52.1

90.4

0.78

41.3

93.8

27.9

96.5

42.5

93.5

54.0

90.1

0.80

37.1

95.1

30.6

96.3

45.7

93.2

57.2

89.5

0.82

33.6

95.7

31.3

96.1

46.5

92.8

58.0

89.1

0.84

30.1

96.4

32.7

96.0

48.2

92.5

59.6

88.7

0.86

22.4

97.9

38.3

95.6

54.2

91.9

65.3

87.7

0.88

20.3

98.1

38.3

95.5

54.3

91.7

65.3

87.5

0.90

14.7

99.6

68.1

95.3

80.3

91.3

86.6

86.9

0.92

10.4

99.8

75.2

95.0

85.2

90.9

90.2

86.3

0.94

7.9

100.0

100.0

94.9

100.0

90.7

100.0

86.0

0.96

3.9

100.0

100.0

94.7

100.0

90.4

100.0

85.5

0.98

0.6

100.0

100.0

94.5

100.0

90.1

100.0

85.1

1.00

0.0

100.0

-

94.5

-

90.0

-

85.0

  1. Prob., probability; PPV, positive predictive value; NPV, negative predictive value