Merikangas KR, Jin R, He JP, Kessler RC, Lee S, Sampson NA, et al. Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Arch Gen Psychiatry. 2011;68:241–51.
Article
Google Scholar
Roshanaei-Moghaddam B, Katon W. Premature mortality from general medical illnesses among persons with bipolar disorder: a review. Psychiatr Serv. 2009;60(2):147–56.
Article
Google Scholar
Chesney E, Goodwin GM, Fazel S. Risks of all-cause and suicide mortality in mental disorders: a meta-review. World Psychiatry. 2014;13:153–60.
Article
Google Scholar
Walker ER, McGee RE, Druss BG. Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis. JAMA Psychiat. 2015;72(4):334–41.
Article
Google Scholar
Kiecolt-Glaser JK, Wilson SJ. Psychiatric disorders, morbidity, and mortality: tracing mechanistic pathways to accelerated aging. Psychosom Med. 2016;78:772–5.
Article
Google Scholar
Lima CNC, Suchting R, Scaini G, Cuellar VA, Favero-Campbell AD, Walss-Bass C, et al. Epigenetic GrimAge acceleration and cognitive impairment in bipolar disorder. Eur Neuropsychopharmacol. 2022;62:10–21.
Article
CAS
Google Scholar
Ballester PL, Romano MT, de Azevedo CT, Hassel S, Strother SC, Kennedy SH, et al. Brain age in mood and psychotic disorders: a systematic review and meta-analysis. Acta Psychiatr Scand. 2022;145(1):42–55.
Article
Google Scholar
Darrow SM, Verhoeven JE, Révész D, Lindqvist D, Penninx BW, Delucchi KL, et al. The association between psychiatric disorders and telomere length: a meta-analysis involving 14,827 persons. Psychosom Med. 2016;78(7):776–87.
Article
Google Scholar
Ochoa ELM. Lithium as a neuroprotective agent for bipolar disorder: an overview. Cell Mol Neurobiol. 2022;42(1):85–97.
Article
CAS
Google Scholar
Pisanu C, Squassina A. Rationale of the potential role of lithium in the antiaging arena. Drugs of the Future. 2020;45(6):397–407.
Article
Google Scholar
Okazaki S, Numata S, Otsuka I, Horai T, Kinoshita M, Sora I, et al. Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder. Transl Psychiatr. 2020;10(1):12.
Article
Google Scholar
Salarda EM, Zhao NO, Lima CNNC, Fries GR. Mini-review: the anti-aging effects of lithium in bipolar disorder. Neurosci Lett. 2021;10(759): 136051.
Article
Google Scholar
Squassina A, Pisanu C, Congiu D, Caria P, Frau D, Niola P, et al. Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients. Eur Neuropsychopharmacol. 2016;26(7):1241–7.
Article
CAS
Google Scholar
Pisanu C, Congiu D, Manchia M, Caria P, Cocco C, Dettori T, et al. Differences in telomere length between patients with bipolar disorder and controls are influenced by lithium treatment. Pharmacogenomics. 2020;21(8):533–40.
Article
CAS
Google Scholar
Martinsson L, Wei Y, Xu D, Melas PA, Mathé AA, Schalling M, et al. Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres. Transl Psychiatr. 2013;3(5): e261.
Article
CAS
Google Scholar
Fries GR, Zamzow MJ, Colpo GD, Monroy-Jaramillo N, Quevedo J, Arnold JG, et al. The anti-aging effects of lithium in lymphoblastoid cell lines from patients with bipolar disorder and controls. J Psychiatr Res. 2020;128:38–42.
Article
Google Scholar
Squassina A, Manchia M, Pisanu C, Ardau R, Arzedi C, Bocchetta A, et al. Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications. Neuropsychopharmacology. 2020;45(13):2229–3223.
Article
CAS
Google Scholar
Fries GR, Zamzow MJ, Andrews T, Pink O, Scaini G, Quevedo J. Accelerated aging in bipolar disorder: a` comprehensive review of molecular findings and their clinical implications. Neurosci Biobehav Rev. 2020;112:107–16.
Article
CAS
Google Scholar
Squassina A, Pisanu C, Corbett N, Alda M. Telomere length in bipolar disorder and lithium response. Eur Neuropsychopharmacol. 2017;27(6):560–7.
Article
CAS
Google Scholar
Coutts F, Palmos AB, Duarte RRR, de Jong S, Lewis CM, Dima D, et al. The polygenic nature of telomere length and the anti-ageing properties of lithium. Neuropsychopharmacology. 2019;44(4):757–65.
Article
CAS
Google Scholar
Powell TR, Dima D, Frangou S, Breen G. Telomere length and bipolar disorder. Neuropsychopharmacology. 2018;43(2):445–53.
Article
CAS
Google Scholar
Wei YB, Backlund L, Wegener G, Mathé AA, Lavebratt C. Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium. Int J Neuropsychopharmacol. 2015;18(7):pyv02.
Article
Google Scholar
Lundberg M, Biernacka JM, Lavebratt C, Druliner B, Ryu E, Geske J, et al. Expression of telomerase reverse transcriptase positively correlates with duration of lithium treatment in bipolar disorder. Psychiatry Res. 2020;286: 112865.
Article
CAS
Google Scholar
Squassina A, Niola P, Lopez JP, Cruceanu C, Pisanu C, Congiu D, et al. MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings. Eur Neuropsychopharmacol. 2020;34:39–49.
Article
CAS
Google Scholar
Squassina A, Manchia M, Chillotti C, Deiana V, Congiu D, Paribello F, et al. Differential effect of lithium on spermidine/spermine N1-acetyltransferase expression in suicidal behaviour. Int J Neuropsychopharmacol. 2013;16(10):2209–18.
Article
CAS
Google Scholar
Lin R, Lopez JP, Cruceanu C, Pierotti C, Fiori LM, Squassina A, et al. Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder. Transl Psychiatry. 2021;11(1):629.
Article
CAS
Google Scholar
Hafez AK, Zimmerman AJ, Papageorgiou G, Chandrasekaran J, Amoah SK, Lin R, et al. A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning. Cell Rep. 2022;38(3): 110282.
Article
CAS
Google Scholar
Spitzer RL, Endicott J, Robins E. Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry. 1978;35:773–82.
Article
CAS
Google Scholar
Endicott J, Spitzer RLA. Diagnostic interview: The schedule for affective disorders and schizophrenia. Arch Gen Psychiatry. 1978;35:837–44.
Article
CAS
Google Scholar
Grof P, Dffy A, Cavazzoni P, Grof P, Garnham J, MacDougall M, et al. Is response to prophylactic lithium a familial trait? J Clin Psychiatry. 2002;63:942–7.
Article
CAS
Google Scholar
Manchia M, Adli M, Akula N, Ardau R, Aubry JM, Backlund L, et al. Assessment of response to lithium maintenance treatment in bipolar disorder: a consortium on lithium genetics (ConLiGen) report. PLoS One. 2013;8: e65636.
Article
CAS
Google Scholar
Squassina A, Costa M, Congiu D, Manchia M, Angius A, Deiana V, et al. Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines of lithium responsive bipolar disorder patients. Pharm Res. 2013;73:1–7.
Article
CAS
Google Scholar
Neitzel H. A routine method for the establishment of permanent growing lymphoblastoid cell lines. Hum Genet. 1986;73:320–6.
Article
CAS
Google Scholar
Lahiri DK, Nurnberger JI Jr. A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res. 1991;19:5444.
Article
CAS
Google Scholar
Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res. 2002;30: e47.
Article
Google Scholar