Mitchell-Olds T, Schmitt J: Genetic mechanisms and evolutionary significance of natural variation in Arabidopsis. Nature. 2006, 441: 947-952. 10.1038/nature04878.
Article
CAS
PubMed
Google Scholar
Alonso-Blanco C, Koornneef M: Naturally occurring variation in Arabidopsis: An underexploited resource for plant genetics. Trends Plant Sci. 2000, 5: 22-29. 10.1016/S1360-1385(99)01510-1.
Article
CAS
PubMed
Google Scholar
Risch N, Merikangas K: The future of genetic studies of complex human diseases. Science. 1996, 273: 1516-1517. 10.1126/science.273.5281.1516.
Article
CAS
PubMed
Google Scholar
Steinmetz LM, Mindrinos M, Oefner PJ: Combining genome sequences and new technologies for dissecting the genetics of complex phenotypes. Trends Plant Sci. 2000, 5: 397-401. 10.1016/S1360-1385(00)01724-6.
Article
CAS
PubMed
Google Scholar
Cavalli-Sforza LL, Feldman MW: The application of molecular genetic approaches to the study of human evolution. Nat Genet. 2003, 33 (Suppl): 266-275.
Article
CAS
PubMed
Google Scholar
Garte S: Locus-specific genetic diversity between human populations: An analysis of the literature. Am J Hum Biol. 2003, 15: 814-823. 10.1002/ajhb.10215.
Article
PubMed
Google Scholar
Rosenberg NA, Pritchard JK, Weber JL, Cann HM, et al: Genetic structure of human populations. Science. 2002, 298: 2381-2385. 10.1126/science.1078311.
Article
CAS
PubMed
Google Scholar
Bamshad M, Wooding S, Salisbury BA, Stephens JC: Deconstructing the relationship between genetics and race. Nat Rev Genet. 2004, 5: 598-609.
Article
CAS
PubMed
Google Scholar
Wright S: The genetical structure of populations. Ann Eugen. 1951, 15: 323-354.
Article
CAS
PubMed
Google Scholar
Eisen MB, Spellman PT, Brown PO, Botstein D: Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA. 1998, 95: 14863-14868. 10.1073/pnas.95.25.14863.
Article
PubMed Central
CAS
PubMed
Google Scholar
Paabo S: The mosaic that is our genome. Nature. 2003, 421: 409-412. 10.1038/nature01400.
Article
CAS
PubMed
Google Scholar
Charlesworth D, Charlesworth B, Morgan MT: The pattern of neutral molecular variation under the background selection model. Genetics. 1995, 141: 1619-1632.
PubMed Central
CAS
PubMed
Google Scholar
Caron H, van Schaik B, van der Mee M, Baas F, et al: The human transcriptome map: Clustering of highly expressed genes in chromosomal domains. Science. 2001, 291: 1289-1292. 10.1126/science.1056794.
Article
CAS
PubMed
Google Scholar
Crawley JJ, Furge KA: Identification of frequent cytogenetic aberrations in hepatocellular carcinoma using gene-expression microarray data. Genome Biol. 2002, 3: RESEARCH0075-
Article
PubMed Central
PubMed
Google Scholar
Husing J, Zeschnigk M, Boes T, Jockel KH: Combining DNA expression with positional information to detect functional silencing of chromosomal regions. Bioinformatics. 2003, 19: 2335-2342. 10.1093/bioinformatics/btg314.
Article
PubMed
Google Scholar
Kano M, Nishimura K, Ishikawa S, Tsutsumi S, et al: Expression imbalance map: A new visualization method for detection of mRNA expression imbalance regions. Physiol Genomics. 2003, 13: 31-46.
Article
CAS
PubMed
Google Scholar
Pollack JR, Sorlie T, Perou CM, Rees CA, et al: Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors. Proc Natl Acad Sci USA. 2002, 99: 12963-12968. 10.1073/pnas.162471999.
Article
PubMed Central
CAS
PubMed
Google Scholar
Levin AM, Ghosh D, Cho KR, Kardia SL: A model-based scan statistic for identifying extreme chromosomal regions of gene expression in human tumors. Bioinformatics. 2005, 21: 2867-2874. 10.1093/bioinformatics/bti417.
Article
CAS
PubMed
Google Scholar
Smith JM, Haigh J: The hitch-hiking effect of a favourable gene. Genet Res. 1974, 23: 23-35. 10.1017/S0016672300014634.
Article
CAS
PubMed
Google Scholar
Grimwood J, Gordon LA, Olsen A, Terry A, et al: The DNA sequence and biology of human chromosome 19. Nature. 2004, 428: 529-535. 10.1038/nature02399.
Article
CAS
PubMed
Google Scholar
Plagnol V, Wall JD: Possible ancestral structure in human populations. PLoS Genet. 2006, 2: e105-10.1371/journal.pgen.0020105.
Article
PubMed Central
PubMed
Google Scholar
Hey J, Nielsen R: Multilocus methods for estimating population sizes, migration rates and divergence time, with applications to the divergence of Drosophila pseudoobscura and D. persimilis. Genetics. 2004, 167: 747-760. 10.1534/genetics.103.024182.
Article
PubMed Central
CAS
PubMed
Google Scholar
HapMap: A second generation human haplotype map of over 3.1 million SNPs. Nature. 2007, 449: 851-861. 10.1038/nature06258.
Article
Google Scholar
Hoehe MR, Timmermann B, Lehrach H: Human inter-individual DNA sequence variation in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics. Curr Pharm Biotechnol. 2003, 4: 351-378. 10.2174/1389201033377300.
Article
CAS
PubMed
Google Scholar
HapMap: A haplotype map of the human genome. Nature. 2005, 437: 1299-1320. 10.1038/nature04226.
Article
Google Scholar
Patterson N, Price AL, Reich D: Population structure and eigenanalysis. PLoS Genet. 2006, 2: e190-10.1371/journal.pgen.0020190.
Article
PubMed Central
PubMed
Google Scholar
Rohlf FJ: NTSYS-pc: Numerical taxonomy and multivariate analysis system, ver.2.11f, Exeter Software, New York, NY. 2002
Google Scholar
Mantel N: The detection of disease clustering and a generalized regression approach. Cancer Res. 1967, 27: 209-220.
CAS
PubMed
Google Scholar
Rechner A: Methods of Multivariate Analysis. 2002, John Wiley Sons New York NY, 270-321.
Google Scholar
Johnson RA, Wichern DW: Applied Multivariate statistical Analysis (4th edn). 1998, Prentice Hall Upper Saddle River NJ
Google Scholar
SAS: SAS Version 9.1. SAS Institute, Cary, NC. 2004
Google Scholar
Hair JF, Anderson RE, Tatham RL, Black WC: Multivariate Data Analysis (5th edn). 1998, Macmillan Publishing Company New York NY
Google Scholar
Ganter B, Giroux CN: Emerging applications of network and pathway analysis in drug discovery and development. Curr Opin Drug Discov Devel. 2008, 11: 86-94.
CAS
PubMed
Google Scholar
Keinan A, Mullikin JC, Patterson N, Reich D: Accelerated genetic drift on chromosome X during the human dispersal out of Africa. Nat Genet. 2009, 41: 66-70. 10.1038/ng.303.
Article
PubMed Central
CAS
PubMed
Google Scholar
Baer CF: Among-locus variation in Fst: Fish, allozymes and the Lewontin-Krakauer test revisited. Genetics. 1999, 152: 653-659.
PubMed Central
CAS
PubMed
Google Scholar
Hammer MF, Mendez FL, Cox MP, Woerner AE, et al: Sex-biased evolutionary forces shape genomic patterns of human diversity. PLoS Genet. 2008, 4: e1000202-10.1371/journal.pgen.1000202.
Article
PubMed Central
PubMed
Google Scholar
Greenwood TA, Rana BK, Schork NJ: Human haplotype block sizes are negatively correlated with recombination rates. Genome Res. 2004, 14: 1358-1361. 10.1101/gr.1540404.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wright S: Evolution and the Genetics of Populations, Vol. 4: Variability Within and Among Natural Populations. 1978, University of Chicago Press; Chicago IL, 1-573.
Google Scholar
Weir BS, Hill WG: Estimating F-statistics. Annu Rev Genet. 2002, 36: 721-750. 10.1146/annurev.genet.36.050802.093940.
Article
CAS
PubMed
Google Scholar
Nei M: Molecular Population Genetics. 1987, Columbia University Press New York NY
Google Scholar
Cavalli-Sforza L, Menozzi P, Piazza A: The History and Geography of Human Genes. 1994, Princeton University Press Princeton NJ
Google Scholar
Deka R, Shriver MD, Yu LM, Ferrell RE, et al: Intra-and inter-population diversity at short tandem repeat loci in diverse populations of the world. Electrophoresis. 1995, 16: 1659-1664. 10.1002/elps.11501601275.
Article
CAS
PubMed
Google Scholar
Hey J, Won YJ, Sivasundar A, Nielsen R, et al: Using nuclear haplotypes with microsatellites to study gene flow between recently separated cichlid species. Mol Ecol. 2004, 13: 909-919. 10.1046/j.1365-294X.2003.02031.x.
Article
CAS
PubMed
Google Scholar
Barbujani G: Human races: Classifying people vs understanding diversity. Curr Genomics. 2005, 6: 215-226. 10.2174/1389202054395973.
Article
CAS
Google Scholar
Witherspoon DJ, Wooding S, Rogers AR, Marchani EE, et al: Genetic similarities within and between human populations. Genetics. 2007, 176: 351-359. 10.1534/genetics.106.067355.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kiambi D, Newbury HJ, Ford-Lloyd BV, Dawson I: Contrasting genetic diversity among Oryza longistaminata (A. Chev et Roehr) populations from different geographic origins using AFLP. Afr J Biotechnol. 2005, 4: 308-317.
CAS
Google Scholar
Stevens VM, Pavoine S, Baguette M: Variation within and between closely related species uncovers high intra-specific variability in dispersal. PLoS One. 2010, 5: e11123-10.1371/journal.pone.0011123.
Article
PubMed Central
PubMed
Google Scholar
Lewontin RC: The apportionment of human diversity. Evol Biol. 1972, 6: 381-398.
Article
Google Scholar
Baye TM: Genetic Diversity Analyses in Populations of Vernonia galamensis. 2004, Cuvillier Verlag Göttingen Germany, 170-
Google Scholar
Jorde LB, Wooding SP: Genetic variation, classification and 'race'. Nat Genet. 2004, 36: S28-S33. 10.1038/ng1435.
Article
CAS
PubMed
Google Scholar
Kachigan S: Multivariate Statistical Analysis. 1991, Radius Press New York NY
Google Scholar
Zar J: Biostatistical Analysis. 1999, Prentice Hall Upper Saddle River NJ, 4
Google Scholar
Qin H, Morris N, Kang SJ, Li M, et al: Interrogating local population structure for fine mapping in genome-wide association studies. Bioinformatics. 2010, 26: 2961-2968. 10.1093/bioinformatics/btq560.
Article
PubMed Central
CAS
PubMed
Google Scholar
Thomas JH: Thinking about genetic redundancy. Trends Genet. 1993, 9: 395-399. 10.1016/0168-9525(93)90140-D.
Article
CAS
PubMed
Google Scholar
Becquet C, Patterson N, Stone AC, Przeworski M, et al: Genetic structure of chimpanzee populations. PLoS Genet. 2007, 3: e66-10.1371/journal.pgen.0030066.
Article
PubMed Central
PubMed
Google Scholar
Casa AM, Pressoir G, Brown PJ, Mitchell SE, et al: Community resources and strategies for association mapping in sorghum. Crop Sci. 2008, 48: 30-40. 10.2135/cropsci2007.02.0080.
Article
Google Scholar
Gardner M, Williamson S, Casals F, Bosch E, et al: Extreme individual marker F(ST)values do not imply population-specific selection in humans: The NRG1 example. Hum Genet. 2007, 121: 759-762. 10.1007/s00439-007-0364-9.
Article
PubMed
Google Scholar
Monreal AW, Zonana J, Ferguson B: Identification of a new splice form of the EDA1 gene permits detection of nearly all X-linked hypohidrotic ectodermal dysplasia mutations. Am J Hum Genet. 1998, 63: 380-389. 10.1086/301984.
Article
PubMed Central
CAS
PubMed
Google Scholar
Sabeti PC, Varilly P, Fry B, Lohmueller J, et al: Genome-wide detection and characterization of positive selection in human populations. Nature. 2007, 449: 913-918. 10.1038/nature06250.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yan M, Wang LC, Hymowitz SG, Schilbach S, et al: Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science. 2000, 290: 523-527. 10.1126/science.290.5491.523.
Article
CAS
PubMed
Google Scholar
Nan H, Kraft P, Hunter DJ, Han J: Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians. Int J Cancer. 2009, 125: 909-917. 10.1002/ijc.24327.
Article
PubMed Central
CAS
PubMed
Google Scholar
Clark AG, Hubisz MJ, Bustamante CD, Williamson SH, et al: Ascertainment bias in studies of human genome-wide polymorphism. Genome Res. 2005, 15: 1496-1502. 10.1101/gr.4107905.
Article
PubMed Central
CAS
PubMed
Google Scholar
Reich DE, Lander ES: On the allelic spectrum of human disease. Trends Genet. 2001, 17: 502-510. 10.1016/S0168-9525(01)02410-6.
Article
CAS
PubMed
Google Scholar
Lowry DB: Landscape evolutionary genomics. Biol Lett. 2010, 6: 502-504. 10.1098/rsbl.2009.0969.
Article
PubMed Central
PubMed
Google Scholar
Wall JD, Cox MP, Mendez FL, Woerner A, et al: A novel DNA sequence database for analyzing human demographic history. Genome Res. 2008, 18: 1354-1361. 10.1101/gr.075630.107.
Article
PubMed Central
CAS
PubMed
Google Scholar
Miller RD, Phillips MS, Jo I, Donaldson MA, et al: High-density single-nucleotide polymorphism maps of the human genome. Genomics. 2005, 86: 117-126. 10.1016/j.ygeno.2005.04.012.
Article
PubMed Central
CAS
PubMed
Google Scholar
Myles S, Hradetzky E, Engelken J, Lao O, et al: Identification of a candidate genetic variant for the high prevalence of type II diabetes in Polynesians. Eur J Hum Genet. 2007, 15: 584-589. 10.1038/sj.ejhg.5201793.
Article
CAS
PubMed
Google Scholar
Ayodo G, Price AL, Keinan A, Ajwang A, et al: Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants. Am J Hum Genet. 2007, 81: 234-242. 10.1086/519221.
Article
PubMed Central
CAS
PubMed
Google Scholar
Myles S, Davison D, Barrett J, Stoneking M, et al: Worldwide population differentiation at disease-associated SNPs. BMC Med Genomics. 2008, 1: 22-10.1186/1755-8794-1-22.
Article
PubMed Central
PubMed
Google Scholar
Redden DT, Divers J, Vaughan LK, Tiwari HK, et al: Regional admixture mapping and structured association testing: Conceptual unification and an extensible general linear model. PLoS Genet. 2006, 2: e137-10.1371/journal.pgen.0020137.
Article
PubMed Central
PubMed
Google Scholar
Campbell CD, Ogburn EL, Lunetta KL, Lyon HN, et al: Demonstrating stratification in a European American population. Nat Genet. 2005, 37: 868-872. 10.1038/ng1607.
Article
CAS
PubMed
Google Scholar
Linhart Y, Grant M: Evolutionary significance of local genetic differentiation in plants. Annu Rev Ecol Syst. 1996, 27: 237-277. 10.1146/annurev.ecolsys.27.1.237.
Article
Google Scholar
Erksson L, Johansson E, Kettaneh-Wold N: Multi- and Megavariate Analysis. 2001, Umetrics Umea Sweden
Google Scholar
McKeigue PM: Mapping genes that underlie ethnic differences in disease risk: Methods for detecting linkage in admixed populations, by conditioning on parental admixture. Am J Hum Genet. 1998, 63: 241-251. 10.1086/301908.
Article
PubMed Central
CAS
PubMed
Google Scholar
Raponi M, Belly RT, Karp JE, Lancet JE, et al: Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia. BMC Cancer. 2004, 4: 56-10.1186/1471-2407-4-56.
Article
PubMed Central
PubMed
Google Scholar
Shriner D, Baye TM, Padilla MA, Zhang S, et al: Commonality of functional annotation: A method for prioritization of candidate genes from genome-wide linkage studies. Nucleic Acids Res. 2008, 36: e26-
Article
PubMed Central
PubMed
Google Scholar